gut.bmj7d
CAF-macrophage crosstalk in tumour microenvironments governs the response to immune checkpoint blockade in gastric cancer peritoneal metastases
Background Peritoneal metastasis is the most common metastasis pattern of gastric cancer. Patients with gastric cancer ...
gut.bmj7d
Recent advances in clinical practice: mastering the challenge—managing IBS symptoms in IBD
Many patients with IBD report persisting symptoms, despite resolution of the inflammatory process. Although by definition, a ...
gut.bmj4d
Devices substitution can reduce environmental burden: what about strategies substitution?
We read with great interest the article by Henniger et al 1 about reducing scope 3 carbon emissions in endoscopy and would like to discuss several points. First, we commend the study’s transparency, ...
gut.bmj23h
Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells
2 Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University School of Oncology, Beijing Cancer Hospital/Institute, ...
gut.bmj14d
Quest for HBV functional cure: what have we learnt from silencing RNAs?
The remarkable success of direct-acting antivirals in curing hepatitis C led to concerted efforts in developing a cure for hepatitis B. Unlike hepatitis C, it is accepted that a sterilising cure is ...
gut.bmj1d
TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function
Objective We explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA overload through the ...
gut.bmj1d
Acute pancreatitis: recent advances through randomised trials
Correspondence to Marc G Besselink, Department of Surgery, Amsterdam Gastroenterology and Metabolism, AMC Amsterdam, 22660, Amsterdam, The Netherlands; m.g.besselink{at}amc.uva.nl Acute pancreatitis ...
gut.bmj3d
British Society of Gastroenterology (BSG) guidelines for management of autoimmune hepatitis
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease which, if untreated, often leads to cirrhosis, liver failure and death. Major advances were made in its management based on ...
gut.bmj7d
Novel strategy for oral peptide delivery in incretin-based diabetes treatment
Objective To fulfil an unmet therapeutic need for treating type 2 diabetes by developing an innovative oral drug delivery nanosystem increasing the production of glucagon-like peptide-1 (GLP-1) and ...
gut.bmj1d
Frequent loss of SMAD4/DPC4 protein in colorectal cancers
1 Department of Medical Genetics and Department of Pathology, Haartman Institute, PO Box 63, FIN-00014 University of Helsinki, Finland 2 Department of Medical Genetics, Haartman Institute, PO Box 63, ...
gut.bmj7d
Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years
Objective The incidence of colorectal cancer (CRC) declines among subjects aged 50 years and above. An opposite trend appears among younger adults. In Europe, data on CRC incidence among younger ...