Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently relatively ineffective in homozygous familial hypercholesterolemia (HoFH). The standard treatment ...

The most common is autosomal recessive, type 1, which is associated with HFEmutations, predominantly C282Y homozygous and rarely C282Y/H63D compound heterozygous. The highest prevalence of C282Y ...

A genetic regulator of tomato sweetness has been identified through comparison of wild and domesticated varieties of the plant. Genetically engineering tomatoes to alter this gene increases sugar ...