2 Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University School of Oncology, Beijing Cancer Hospital/Institute, ...

1 Department of Medical Genetics and Department of Pathology, Haartman Institute, PO Box 63, FIN-00014 University of Helsinki, Finland 2 Department of Medical Genetics, Haartman Institute, PO Box 63, ...

Objective We explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA overload through the ...

Correspondence to Marc G Besselink, Department of Surgery, Amsterdam Gastroenterology and Metabolism, AMC Amsterdam, 22660, Amsterdam, The Netherlands; m.g.besselink{at}amc.uva.nl Acute pancreatitis ...

Objective An international meeting was organised to develop consensus on (1) the landmarks to define the gastro-oesophageal junction (GOJ), (2) the occurrence and pathophysiological significance of ...

Introduction Entonox is a safe and effective method of analgesia used for patients undergoing colonoscopy. It has a number of advantages over sedo-analgesia and is available for use in a large number ...

Dr J A Williams, Department of Physiology, University of Michigan Medical School, 7744 Medical Science Building II, Ann Arbor, MI 48109-0622, USA. jawillms{at}umich.edu Arginine induced acute ...

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease which, if untreated, often leads to cirrhosis, liver failure and death. Major advances were made in its management based on ...

Studies were carried out to investigate the mechanisms underlying the reduction of hepatocellular necrosis observed when polyunsaturated phosphatidylcholine was administered to patients with HBsAg ...

2 Department of Medical Genetics, University of Helsinki, Finland, and National Public Health Institute, Department of Molecular Medicine, Helsinki, Finland 3 Hospital for Children and Adolescents, ...

Introduction SB17 is a proposed biosimilar to ustekinumab reference product (UST-RP), which is a fully human IgG1/kappa monoclonal antibody to interleukin (IL)-12/23. In accordance with FDA and EMA ...

2 NIHR Biomedical Research Centre at Guy's and Saint Thomas' NHS Foundation Trust and King's College, London, UK The prevalence of IBD is rising in the Western world. Despite an increasing repertoire ...